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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc42fc207aa33325a1d429e9268b57f3828788f3d72b6ed4dbe48eee0e2463a2' 
  AND token = '1FJ+qMWjYlaMfkhMuL1+ebfyPyZbqaJkTLK/LX/C61s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}