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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf52a7b29fa2f7e4cc957ca2eb806c081757710c088a7e9eded6489bdf0d5dd4' 
  AND token = '4xFlIIPdjvAeUTu8nR6WjudE0WWKe0PqIkrf6w6+I3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}