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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f90a3c446635fb115089e00e3c34483dd0cc21bed27fd21e4e1c2ab5f43bbcb9' 
  AND token = 'DZ2CQjopg13x4t3OY1U4ludK5/w4APxGh8l31EFF0bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}