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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397acc71ff3def0e9fed1a33867a600b772e8d27c77bb34e764c9ee373582193' 
  AND token = 'X1kV7x+q+xpFDUSDPCO5F0Uf27wSLYqmXiDCKnarfJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}