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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258e2db467dfdedfc1dace0ceba9429426d4d8552e4934e5641bae475f816ef5' 
  AND token = 'tMgF2OJpotJzyyeI3lXetcY2o4Luv4NO0ywx6VYbCp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}