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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5346e58c86a18f058ee6ccf1df24ffc0f2fa469e7e12b9d3a05017f55a090117' 
  AND token = '0NY4vQ/lFvvsnMrBtZ/MipF85Id9A8d4qbKg7Ow9CWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}