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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac77c477b165b65951c72ded25f93a9aaf47a8fac544f95b81be819f148d8905' 
  AND token = 'f42/LtjGAHNFmFsUd5ZXdzAmU7+d4RKaJIJetG5Lg+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}