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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6a566922f26a2a2b29ecea8c6d27d90a7b40827a53ef21ae69a99763216647a' 
  AND token = 'ceBp2W5EWks6/XLYPD0ZAso+Vozfaq30/MzuZiOoID4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}