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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243901daee07926c3e30616619a7e671144a47f385479b7a4cc19bf75953c9b2' 
  AND token = 'BYJNs6WR74eT+6IVbiKdaa6AAd3UVN8Q5drIMsXoWoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}