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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14b80d88357709d640259708c34e89b71249dd4ef4f0985188f26ea8622fa564' 
  AND token = 'nsLE2y/LFRvId2OKJITshxoPDelpcrptXkyEKCkeEh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}