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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eacad82d3314028b0ec42b546b3bb2f2fc521ac55fbd4bb3b54690e649aa13b5' 
  AND token = 'Aw8Ee32HNcz+bfAzdMeY59djJguLQYVjeUv9YwvecDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}