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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '994ecc9bdfcd398237e4a77f5010f0f019a98447e33c5064e360b0a808c2fcf2' 
  AND token = 'dDAPY1aHybzMOxgnPXCG7hDOmsb2+Zv1J8mvW69z3Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}