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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37bdca256fb6f92e85c75fadc8608ee220efed528fab81dc949cbedf2fe22fff' 
  AND token = 'ZkETTcZpJAbjpwbLxWw7+X1XuIC/D8IuwOaC1GeeC78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}