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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74571a7a1ae58a57ebaf22f99129d9fc26e662cca3b9c9f5a2806f0f2be755df' 
  AND token = '78RJbYopwt8SS6G0q2xY+yx7pfL4rBAcLwn/fkI46nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}