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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0961e2e57879bcce1035351a412ea8145e01a8b9b5b910f13762d98a1a8f857' 
  AND token = '+46mquDlWOzKvPutQqkNe+MgYGrrwonLPPtdszyEEAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}