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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def5c02c495c5949872280cfa1977223ad4e8b4cd9da9fe8ab5b16dcc14f5414' 
  AND token = 'RKGNp57Tuig1am3SGU/3sD+oplmzk04T5Qc3t/5BqNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}