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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427b50e0d62cf36ee0b325009e712cdcfd9bf1070db0ef792f78aa3aeda7d95b' 
  AND token = 'hKIUVQcaUnogNZixex1R6EpgV/IG89toaRG179aVrkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}