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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22e43a20ab12aeafc5a9f928e955d7bc8f75e14aafc8343555db1ed98b827b4' 
  AND token = 'TlqGXZO/vBFD1I6x8tixELTAX/slUpcGVSurWnnL1G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}