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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659dc8b5e6fb7a430f5d5e3c28c8add2243f49fdc698f27293317351f8dc317d' 
  AND token = 'P67+8Sg6OSTbIbM9Gx2+psvONf/PsqrXNnw5wGXaL28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}