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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2afa7a5b0f1d66e7dcf48a7ba6493cf48f4e59fbf3534f1a07ee71ec8ac8bf6c' 
  AND token = 'xhZm2CZYoRDGB1R1kdYs0km07njTTRZlC4vytRbpt/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}