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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a220df30b28684d5aeb4ecfc18a5722d96293dadcab149fbcd7812b1ccf0f7f3' 
  AND token = 'lMlQCmrK2qmssdUbl36rBBJAQDMUW5FK9FVCr2SOcfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}