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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74317cae1d8324bec2e54f085f58012da752835b5017df2d8629a02d44b443ee' 
  AND token = 'nkIt7Bva7TAUME2NDL/mnKPT5+B0Sscosg1HHcFV6IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}