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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cc21d48ae8ee4868933ff2d91e70010c82e799ead97492142cfa6372149668' 
  AND token = '0HmZFFIUhkQkj4SmEWjpoEghBy6sUfgeYr5IzLCDBog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}