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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78bee587efab6137e4c944ca262ca80a1651ba4e1beaede9fcf4a3bf4e316e5' 
  AND token = 'Ej+fu3p/AizVX9OiN4E1gr+IvMZuX9hnbyyteUOP6wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}