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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fdd0d237438ab2a5b12b85779b4213f973a6aa0ca8d9e69b51092a14d80d85' 
  AND token = 'v/25Ax9WiXcybSmxc0RcOBPyvvwOB8PUY4pCFzJ6Nvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}