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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493a3d392c1b0eeb89559806429b211a52e72b68d7a3a4922f1e76ee448c9e61' 
  AND token = 'T8uxPxE+XUTWwIa31fgwR8zoN23oDqP7kJlIsIzR8OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}