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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29ca1e426a2b660292b2d78a6ccf01fd4f4b2f3394425d06b87fb2618b1b9a3' 
  AND token = '/VbbCuWRHRDy8JJVCNWr/4BA5KfEaDf4fZ+PhIF87A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}