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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60293aa75cd0909413526e60c886d7a75945ab1514bac50c4b17cc8a90662c21' 
  AND token = 'mC0+aamxGWlv7hafSMV6uE0WisozLdEb0zxEAke4cKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}