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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a409609954d1aa0e726b4029ece13f5c83ec3ee6e110fd33c9104925d4aacee9' 
  AND token = 'd/KhomwT+NYoc3CamexHv/OJloIGSUEn+ynJhMlSYxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}