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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec3c41751f44c7f0fac299c7c1e50ab28f386825dfc9a022e3f0e965a7aa2ad' 
  AND token = 'qcTz5MWSxZWKhsyt5RnT16Fk5umPyEUvF4aMR3KnYss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}