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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c9d7dc2baf70c4d0689ef519edbb7da588e3bc2d3b771edcea2138123a707d' 
  AND token = 'YDjkd/7dZVT6duhoWA1p2K0CkKw33Hoe5Laj1c5W0OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}