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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d1eceec7639c112b1cebbf8df62760e4d440835e538f4e1d074e5e530be31b' 
  AND token = 'qFo1Z3wjyGnwcPLYwfXReuDrEifqRIAeY4YxS9KwT+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}