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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f157ad1628bad8aca073e9142391713260ca7796e7f9b0e34ac9e6ef098e7a7' 
  AND token = 'wv5y2QH+sP/I61PfRNnrG+IiMM7Peo79X8iUoNc3kOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}