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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82395d04ef179a3db4e8c1115da1e923750e19cdc224929a836838656015df59' 
  AND token = 'y4mKJbiuvBlWF1VwCRLa0NBYvaW2rUJcgNP9YLSx14s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}