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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffa854b89386192987797319c26ee84b61d21bcad243007bca160297a26575a0' 
  AND token = 'A4EI3G9/X3khA39P4D6QbW4w2xSo5nOzVkG6hBPlS20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}