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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b24bbcf23496fc91806548fd7f792c4eefee6ee7ff1e50de912754dbebd0da' 
  AND token = 'VeYLrFX0l3OHC4801uYS9sOwArb9XCw8b7/ZK9BW60Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}