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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ecc9906f7660e886c0bf0f9943db7e49b58343c5822e1387b3297fd3f1fea5' 
  AND token = 'VLJgP4wJdUkcJgwED9fLyPoKAxfHVqmTouYivNEg91A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}