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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8901d278af219bcd8d38e78028c397b302b967221441d5eab490afe4872638d1' 
  AND token = 'm+fROkSwhPcSR2kAO8XPn4OacZYl+LS4EKJm5olplmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}