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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4108a1b0a2e4638dcd89f20755d4cd4068682fc855085f941de41cf93f49d7af' 
  AND token = 'w9MeWN9z6oxIquD5YOJ4FMcKwit0Z0YXh2FXf9CVtKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}