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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54163abf40d4e97958188dde264a631d5d89623d65aeaecb14aa6fd8cef7788' 
  AND token = 'eQ7eh3msxMI5MALdsgawsXX7NRtp9GJ3Kqud0v5aKQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}