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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7fb2084a84947642e2af8e862ee548a404681c677d488b223e8144dc3e0421' 
  AND token = 'FNA7Y8I5ujYJ4uGJhkTcnwUdIVk3ytjG2Y6sfv77X/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}