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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bc945076cf7964c0c5520cc4551f100a5cd69534aeb0c46fccb8dfc197a00d2' 
  AND token = 'PEchQeNfvd6xtqWukHYpxQImqkrcT8VPk8NZTWtjd7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}