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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ae5c7602cf375e30bc3e7eadd7f670b418093b3ffc64e0c0185c67ff792a2a' 
  AND token = 'v8PzgxdbM2oeYS9nGrXe+IW7d7akmdlSSK0qvjDT+XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}