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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9072cb9026021142ec295df40bf7b02e1864c34f1325d8e5f7b975c2487588e' 
  AND token = 'DSdQ8Hrhc9PQ4elwYkrf4odhVsY9SxuHyxjtEOvTBKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}