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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2914ad9be2d61d3b1ee3da6affdcd1339efbc5586d9ba0fde051a41240a95def' 
  AND token = '8QqBuH2rxJx+6phaWpogFaZjeN1MYhIEKMmHK0sStms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}