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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1ea6a705609e013478ef20ade179148808d28f2482e9777ab02152094552a3' 
  AND token = 'fNA19Ha8LvZIVfL/3ZkktgTyz9NWXYfpcbwNcqKC4fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}