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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a26b77ab0453fbd167883524d7ee77a8a69901b846f186fe6a258b5cf014d5c' 
  AND token = 'BU3cWSCL8/l0h5mIiKE8895a6qTenW/5JR4CTrhICRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}