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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe1601b7e8228d1d3efa0b9d9a87af7bf1a0976b5a2543f1486cbf480b881d2' 
  AND token = 'PIT9hpxCPWLi/BT4VD1l5AnncXVfqQZjZvdeS8oAWqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}