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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2208e2d2d2396b0a20107adeae47d0ad3e42b19f48e5aa43c45c38cdc11aa17a' 
  AND token = 'LdfExzJTQ+zD/qDSUmsHGfCh9EV2G6TWJkFuuU/a2TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}