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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c805a41fa0c2579b5a30b08bbca1b8deb24c9b36b53dfe65c15783c311187c' 
  AND token = 'zsc4thiHQDnBlMzA5CnaCjzKpBD1oX8BfKN3TTa35Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}